Dermazin Cream: Composition, Uses, Dosage, indications, contraindications, Side Effects, Price

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Each 100g of dermazin or dermazene cream contains 1g of micronized silver sulphadiazine in a hydrophilic base.

Mechanism of Action:

Dermazin is a local chemotherapeutic for prevention and treatment of burn wound infections.

Silver sulphadiazine disintegrates in the burn wound thereby causing a slow and sustained release of silver ions. Silver ions bind to the bacterial desoxyribonucleic acid, thus inhibiting the growth and multiplication of bacterial cells and subcutaneous tissue.

Dermazine cream has a broad antibacterial spectrum including virtually all microbial species likely to infect the wound: E coli, Pseudomonas aeruginosa, Staphylococcus aureus, strains of Proteus and Klebsiella, it is also effective against candida albicans and other fungi.

Dermazin Cream: Composition, Uses, Dosage, indications, Side Effects, Price
Picture of dermazin cream

Dermazin penetrates into the necrotic tissue and exudate. This effect is very important in view of the fact that systemic antibiotics are not effective against the bacterial flora of the avascular burn necrosis.

Indications/Uses of dermazin

Dermazin cream used for?

Treatment and prevention of burn wound infections and infected dermal defects, including bed sores and deep neglected wounds.

Dermazin can also be used for dressing of chronic leg ulcers.

#Dermazin provides relief for sunburns and secondarily infected pimples.

#Dermazin cream is good for dressing grade 1 and grade 2 bed sores


The use of of dermazin is contraindicated in premature infants and neonates because of possible kernicterus.

Dermazin should not be used in pregnancy, except in cases when the potentially life saving benefits of the medication outweigh possible hazard to the fetus.

Dermazin is for topical use only and should not be taken orally.


Caution is required in the presence of hypersensitivity reaction to sulphonamides because of possible allergic reactions, in patients with inborn glucose-6-phosphate dehydrogenase deficiency, as hemolysis may occur after the application of cream to the large body surface area, as well as in the presence of hepatic and renal dysfunction.

When treatment with dermazin cream involves prolonged administration or large burn surfaces, the white blood cell count should be monitored, as leukopenia may occur.


Elevation of body temperature occuring in children during the first days of treatment is unrelated to dermazin administration and should not lead to the discontinuation of therapy.


In prolonged treatment of burn wounds involving extensive areas of the body, the serum sulphonamide concentrations may approach the levels equal to those in systemic treatment.


How to use dermazin cream

An appropriate treatment regimen is promptly instituted after evaluating the extent and depth of the burn wound. After the burned area is cleaned and debrided, dermazin cream is applied to a thickness of 2-4mm to the burned area or, preferably, the cream is applied to the sterile gauze which is placed ove the burn wound. The cream is applied by a sterile spatula or gloved hand.

The burned areas are usually covered with the cream once daily; in severe burn wounds the cream is reapplied daily. Duration of superficial burn treatment depends on the injury ranging from several days to one month at the most.

Surgery is required only if no healing occurs after one month of treatment with dermazin.

Prior to each reapplication of the silver sulphadiazine cream, the burn should be washed in shower or with an antiseptic solution to remove remnants of cream and wound exudate which are abundant after dermazene application., resembling pus in colour but actually antiseptic.

Dermazin cream in jars intended for repeated application in one patient only. The application of the cream is painless. It does not stain clothes and bed linen.


Tubes of 25g of cream

Tubes of 50g of cream

Jars of 250g of cream

Jars of 500g of cream


The price of dermazin cream is about $1 (#700 naira)

And now to answer some of your frequent questions


Is dermazin cream good for stretch marks?

The answer is no. #Dermazin is an antibiotics and stretch mark is not a bacteria infection….

Dermazin cream for sunburn?

Yes, sunburn is just like a superficial thickness burns….dermazin helps to soothe the pain and regain the skin color.

Is dermazin good for scars?

The answer is no…dermazin does not remove or reduce is not a steriod.

Is dermazin cream good for a acne or pimples?

The answer is yes if the acne is infected. Just apply the #dermazin cream on the inflammed and painful acne to help remove the infection. Please notebthat dermazin does not clear your face of acne though.

Does dermazin clear eczema?

The answer is no…dermazin is not a steriod so cannot help remove eczema….Eczema is a group of conditions that make your skin inflamed or irritated.

The most common type is atopic dermatitis or atopic eczema. β€œAtopic” refers to a person’s susceptibility to get allergic conditions such as asthma and hay fever. Dermazin is no cure for eczema.

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