FEJERON Blood Tonic: Uses, Composition, Side Effects and Indications.
Composition: *IRON + VIT. B12 + FOLIC ACID*
Each 5ml contains:
Ferric Ammonium Citrate U. S. P. 80mg.
(Equivalent to 17.2mg elemental Iron)
Folic Acid B. P. 500mg.
Vitamin B 12 B. P. 5mcg.
Clinical Pharmacology
Fejeron blood tonic is rich in the iron salt, Ferric Ammonium Citrate and contains Vitamin B12. Ferric Ammonium Citrate is best – tolerated iron supplement.
It provides an optimum tolerance of the iron preparation, which is of utmost importance in maintaining long term patient compliance to any hematinic therapy.
It rapidly supplements el thus leading to faster correction of anaemia and replenishment of tissue iron stores.
Folic Acid has antagonistic property.
It aids cell division and the normal production of red blood cells including maturation of megalobast into normoblast.
Vitamin B12 is required for proper red blood cells formation, neurological function, and DNA synthesis.
It functions as a cofactor for methionine synthase and L-methylmalonyl – CoA matase.
Methionine synthase can catalyze the conversion of homocysteine to methionine. Methionine is required for the formation of S-adenosylmethionine, a universal methyl donor for almost 100 different substrates, including DNA, RNA, hormones, proteins, and lipids.
L-methylmalonyl – CoA mutase converts L-methylmalonyl – CoA to succinyl – CoA in the degradation of propionate, an essential biochemical reaction in fat and protein metabolism. Succinyl – CoA is also required for hemoglobin synthesis of elemental Iron so that iron deficiency is quickly controlled.
*INDICATIONS and Use:*
Fejeron Blood Tonic is indicated in iron deficiency anaemia cause by trauma, surgery hookworm infestation, child delivery, menstruation and dietary deficiency ; in situations of increased iron demand as in pregnancy, lactation as well as in growth children and for the elderly with the problem of poor iron ingestion or absorption.
It is also indicated in convalescence from prolonged and debilitating illness with symptoms such as weakness, lack of concentration, lassitude, pallor and tiredness, anaemia due to febrile illness like malaria, typhoid and influenza.
*Contra-indications:*
Fejeron should not be given to patients receiving repeated blood transfusions or to patients with anaemia and should not be administered concomitantly with parenteral Iron. It helps build blood and boosts immunity.
*Dosage and Administration:*
Children (6-12 years): 5ml two times daily.
Adults: 5ml-10ml two times daily.
Pregnancy and stress: 5ml two times daily.
Or as prescribed by the physician.
*Precaution:*
Fejeron may cause a black discoloration of the stool, this is normal with iron preparations.
*Side – Effects:*
Fejeron is usually well tolerated, however, there may be a few cases of gastro-intestinal upsets due to iron intolerance. This may be minimized by reducing the dosage and also by administering after meals.
*Adverse Reactions:*
Only the side effects indicated are likely to be encountered at the recommended dosage levels.
Adverse reactions observed when this preparation is taken in large doses include epigastric pain, diarrhea, vomiting, haematemesis and circulator failure.
*Overdose and Antidote:*
If overdose is suspected contact your doctor immediately.
In acute poisoning, wash out the stomach with a 1% sodium bicarbonate solution and then give 5 to 10g of Desferroxamin Masylate in 50 to 100ml of water by mouth, or by stomach tube to chelate any iron left in stomach and prevent further absorption.
If Desferroxamin Masylate is not available, empty the stomach immediately by emesis and lavage using 1 to 5% solution of sodium bicarbonate, and leave up to about 300ml of the solution in the stomach ; sodium bicarbonate from poorly absorbed ferrous carbonate with any ferrous iron.
*Presentation:*
Pack of 100ml, 200ml and 1 liter
*Warning(s):*
Do not use this preparation for other health conditions. Keep medicine away from children.
*Storage Conditions:*
Store below 30°C. Keep away from light.
