Multivitamins reduces the efficacy of antimalarials-expert

Breaking the figures further, she said there are more reported cases of malaria in children under five years and in pregnant women where the infection can be very serious due to the very vulnerable nature of these two segments of the population.

Dr. Adejumo said this while speaking at the Association of Hospital and Administrative Pharmacists of Nigeria (AHAPN) 2019 World Malaria Day celebration at Bariga Local Government Hall, Bariga, with the theme: “Zero malaria starts with me.”

She stressed that the theme is apt at this time in view of the collective responsibilities of all stakeholders, including the governments at all levels, professional bodies, healthcare workers at all levels, civil society organisations, communities, corporate organisations  and even individuals to reduce the scourge of malaria. While explaining that the topography and ecologic features of the state, the abundant coastal features, rapid urbanisation and poor drainage are some of the major factors that contribute to the all-year transmission of malaria, she said over the years, the state government has demonstrated continued commitment to the control of malaria.

Dr. Amibor said there are five ACTs available for use against plasmodium falciparum malaria, adding that the choice of ACT should be based on results of therapeutic efficacy studies against local strains of plasmodium falciparum malaria.

He listed the ACTs recommended by WHO to include, Artemether-lumefantrine (AL), Artesunate-amodiaquine (AS-AQ), Artesunate-mefloquine (AS-MQ), Artesunate–sulphadoxine-pyrimethamine (AS-SP) and Dihydroartemisinine-piperaquin (DHA-PQP).

Despite reported cases of relapse after use, Dr. Amibor insisted, ACTs remain the mainstay of treatment for plasmodium falciparum since there are no alternatives to artemisinin derivatives for now. He cautioned Nigerians to not take multivitamins containing vitamin C with the ACTs as they render them less effective if taken together.

“A Nigerian study involving 80 malaria infected adult patients showed that co-administration of orange juice, grapefruit juice or vitamin C concomitantly with artesunate or amodiaquine severely diminished the efficacy and potency of the drugs,” he said.

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